Notre Dame researcher to study dengue virus vaccine

Author: Brandi Klingerman

Guido FeaturedGuido Camargo España

Guido Camargo España

Guido Camargo España, postdoctoral research associate of biological sciences, has received a Postdoctoral Training Award inTranslational Research from the Indiana Clinical and Translational Sciences Institute (CTSI). The fellowship is designed to provide an “opportunity to be mentored in research-intensive multidisciplinary settings toward the goal of developing careers in translational research.”

Camargo España received his fellowship for work with Alex Perkins, Eck Family Assistant Professor of Biological Sciences at Notre Dame and affiliated member of the Eck Institute for Global Health, and Timothy Endy, professor at State University of New York. For the project, he will conduct simulation modeling to estimate dengue vaccine profiles from trial results. 

Currently, there is a dengue vaccine that has shown efficacy in treating patients who have already been infected with the dengue virus. However, the same vaccine, when given to those who have never contracted the dengue virus, can have harsher effects if those people eventually contract the virus.

“There are certain unobservable variables affecting dengue vaccine trials,” said Camargo España. “Therefore, our goal with this research is to simulate these trials using agent-based computational models to better understand what those variables are and how they impact our estimates of the effect of the vaccine.” 

The Postdoctoral Fellowship in Translational Research offers funding for one year and the potential to renew the fellowship for one additional year. To learn more about this award and other Indiana CTSI funding opportunities, please visit https://ctsi.nd.edu/funding/

The Indiana CTSI is a statewide collaboration of Indiana University, Purdue University, and the University of Notre Dame, as well as public and private partnerships. Established in 2008, the Indiana CTSI is supported by a $25 million Clinical and Translational Science Award from the National Center for Advancing Translational Sciences (NCATS) of the National Institutions of Health, supplemented by nearly $60 million from the state, the three member universities, and public and private partnerships. The Indiana CTSI is a member of a national network of CTSA-funded organizations across the United States.

Originally published by Brandi Klingerman at ctsi.nd.edu on October 19, 2018.